Advancing the Future of Long Non-Coding RNA (IncRNA) Medicine

Developing first-in-class therapies to precisely target disease-driving long non-coding RNAs (lncRNAs) in oncology and beyond
SCIENCE

LncRNAs: A Vast and Largely Untapped Therapeutic Landscape

Traditional drug development has focused on the ~2% of the genome encoding proteins, leaving ~98% — largely non-coding RNAs, including lncRNAs.
Predominantly uncharacterised, yet a handful of lncRNAs linked to major human diseases.
No approved drugs target lncRNAs — the opportunity to create next frontier first-in-class lncRNA medicine.
Traditional drug development has focused on the ~2% of the genome encoding proteins, leaving ~98% — largely non-coding RNAs, including lncRNAs
Largely uncharacterised, yet a handful of lncRNAs linked to major human diseases
No approved drugs target lncRNAs — the opportunity to create next frontier first-in-class lncRNA medicine
APPROACH

Turning lncRNA Biology into Precision Medicines

We employ systematic strategies and integrated proprietary platforms to discover, prioritise, and functionally characterise disease-relevant lncRNAs, and to target them with precision and effectiveness.

AMRQ-ARCANA

01
An advanced computational engine that discovers and prioritises disease-relevant lncRNAs.

AMRQ TARGET ID ATLAS

02
A curated atlas of functionally validated and high-confidence disease-relevant lncRNA targets.

AMRQ Drug Discovery (DD)

03
A dedicated drug discovery and development program focused on creating effective therapies that target pathogenic lncRNAs.

Amaroq is Focused on High-Quality Programs for Oncology First

Oncology programs are prioritised based on high unmet needs with best-in-class potential geared towards reliable delivery to specific organs, tissues and cells of interest.

PIPELINE

ONCOLOGY
Undisclosed Target 1
D
P
IND
Ph1
Ph2
Ph3
ONCOLOGY
Undisclosed Target 2
D
P
IND
Ph1
Ph2
Ph3

Core Team Members

Core Team Members

Dr Partha Das
CSO, Amaroq Tx
ex-Flagship Pioneering; ex-PI (currently Adjunct) Monash University; ex-Harvard: 20+ years of global experience across academia and industry, with deep expertise in RNA biology, epigenetics, gene regulation, and functional genomics.
Dr Hong Liu
Advisor & Contractor
ex-NextRNA, Takeda, Sanofi: Expert in computational genomics, systems biology, oncology and lncRNA discovery.
Dr Sarah Meidinger
Operations Manager, Amaroq Tx
ex-TamoRx and Upside Biotechnologies: Experienced biotech startup operations and project manager with a PhD from the University of Auckland.
Dr Sarah Herridge
Founder & Advisor
Director BioNTech; ex-PI Otago University, Founder & ex-CSO Amaroq: 20+ years experience in IncRNA and oncology research.

Board of Directors

Board of Directors

Dr Phil Kearney
Board of Director Chair
ex-Merck, Santaris, Axelia Oncology: 25+ years of biotech leadership across oncology, RNA therapeutics, and licensing.
Aizaz Syed
Board of Director & Senior Investment & Portfolio Manager, Tenmile
ex-Merrill Lynch: 10+ years of investment experience and venture capital, biotech and healthcare investing, investment banking; oversees investment, strategic growth, and partnerships for Amaroq.
David Christensen
Board of Director & CEO, Otago Innovation
20+ years of experience in commercialisation, banking and finance.

Scientific Advisory  Board (SAB)

Scientific Advisory Board (SAB)

Dr Henrik Oerum
CSO, Civi Biotech; ex-Santaris & Exiqon, Roche
ASO expert and drug developer.
Prof David Spector
Professor, CSHL
World leader and 40+yrs research experience in lncRNAs and cancer biology.

Our partners
& investors

Our partners  & investors

Our partners  & investors